Ewha Med J.  2017 Apr;40(2):71-76. 10.12771/emj.2017.40.2.71.

Change in Subfoveal Choroidal Thickness after Argon Laser Panretinal Photocoagulation

Affiliations
  • 1Department of Ophthalmology, Ewha Womans University School of Medicine, Seoul, Korea. ytkim@ewha.ac.kr
  • 2Department of Ophthalmology, Hanyang University School of Medicine, Seoul, Korea.

Abstract


OBJECTIVES
To evaluate changes in subfoveal choroidal thickness (SFCT) and macular thickness as measured by enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) after argon laser panretinal photocoagulation (PRP) in patients with severe diabetic retinopathy.
METHODS
This prospective, comparative case series included 21 patients (28 eyes) with severe diabetic retinopathy. All patients underwent three sessions of PRP. The SFCT and macular thickness were measured using EDI-OCT at baseline and one week after completion of 3 sessions of PRP.
RESULTS
SFCT before PRP was 318.1±96.5 µm and increased to 349.9±108.3 µm; P=0.001 after PRP. Macular thickness significantly increased at one week after PRP from 273.1±23.9 µm at baseline 295.8±25.3 µm at one week; (P<0.001). No significant relationship between the changes in macular thickness and SFCT was observed (r=−0.13, P=0.52).
CONCLUSION
PRP induced increases in both SFCT and macular thickness. Changes in SFCT did not correlate with changes in macular thickness.

Keyword

Choroid; Diabetic retinopathy; Tomography, optical coherence; Macular edema; Photocoagulation

MeSH Terms

Argon*
Choroid*
Diabetic Retinopathy
Humans
Light Coagulation*
Macular Edema
Prospective Studies
Tomography, Optical Coherence
Argon

Figure

  • Fig. 1 Retinal images of a 47-year-old man with bilateral proliferative diabetic retinopathy. (A) Fundus photograph before panretinal photocoagulation shows no abnormalities on fovea centralis. (B,C) Enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) images of the left eye at baseline (B) and one week after completion of panretinal photocoagulation (C). Note that both subfoveal choroidal thickness and central subfield thickness increased from 322 µm to 360 µm and from 294 µm to 312 µm, respectively. Arrows indicate the site of measurement of choroidal thickness.

  • Fig. 2 Subfoveal choroidal thickness (SFCT) and central subfield thickness (CST) measurements at baseline and one week after panretinal photocoagulation (PRP). Optical coherence tomography revealed a statistically significant increase in SFCT and CST one week after PRP.

  • Fig. 3 Change of subfoveal choroidal thickness observed in individual subjects. PRP, panretinal photocoagulation.

  • Fig. 4 Scatter plot showing changes in subfoveal choroidal thickness (SFCT) and central subfield thickness (CST). A significant linear correlation between changes in SFCT and CST is not noted (r=-0.13, P=0.52).


Cited by  1 articles

Changes in Choroidal Thickness after Panretinal Photocoagulation in Diabetic Retinopathy Patients
Sung Yu, Yong Il Kim, Kyoo Won Lee, Hyun Gu Kang
J Korean Ophthalmol Soc. 2016;57(2):256-263.    doi: 10.3341/jkos.2016.57.2.256.


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