Korean J Infect Dis.
2000 Dec;32(6):470-473.
Hepatosplenic Tuberculosis Mimicking Disseminated Candidiasis in Patients with Acute Leukemia
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Catholic University, Seoul, Korea. symonlee@cmc.cuk.ac.kr
Abstract
- The intensive chemotherapy for acute leukemia is often associated with profound, protracted neutropenia and increases the risk of serious infections. In general, the duration of neutropenic period correlates with the increased risk of fungal infection and multiple hepatosplenic microabscesses following neutropenic periods has been one of the major problems in patients with acute leukemia, often attributed to fungal infections such as hepatosplenic candidiasis or disseminated candidiasis. But recently we experienced two cases of hepatosplenic tuberculosis in patients with acute leukemia during or after chemotherapy following prolonged neutropenia. Tuberculosis should be considered as one of causes of hepatosplenic abscesses during prolonged neutropenia, especially in countries, where the disease is endemic.
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