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Angiosarcoma of the Breast and Spleen: A Case Report with Imaging and Pathologic Findings

Kim J, Jung HK, Kim W

Angiosarcoma of the breast is a rare malignant sarcoma of endovascular origin that presents with various radiological findings. We encountered a case of angiosarcoma of the breast presenting as an...
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A Comparative Study on the Advantages of Using a Stapling Device in a Splenectomy for Patients with Traumatic Splenic Injury

Choi SH, Yoo YS, Mun SP

Purpose: Surgery is prioritized for a splenic injury when the patient is hemodynamically unstable or the injury is severe and there is an increased risk of bleeding. This study aimed...
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Effect of pregabalin on nociceptive thresholds and immune responses in a mouse model of incisional pain

Park JH, Cho SH, Kim R, Na SH, Kang Es, Yeom My, Jang Y

Background: It is known that some analgesics as well as pain can affect the immune system. The aim of this study was to investigate the analgesic effect and immunomodulation of...
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Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation

Youn YJ, Lee YB, Kim SH, Jin HK, Bae Js, Hong CW

Patients with severe coronavirus disease 2019 (COVID-19) demonstrate dysregulated immune responses including exacerbated neutrophil functions. Massive neutrophil infiltrations accompanying neutrophil extracellular trap (NET) formations are also observed in patients with...
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Protection of palmitic acid treatment in RAW264.7 cells and BALB/c mice during Brucella abortus 544 infection

Bernardo Reyes AW, Ngoc Huy TX, Vu SH, Kim HJ, Lee JJ, Choi JS, Lee JH, Kim S

Background: We previously elucidated the protective mechanism of Korean red ginseng oil (RGO) against Brucella abortus infection, and our phytochemical analysis revealed that palmitic acid (PA) was an abundant...
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Torsion of a Wandering Spleen Treated by Laparoscopic Surgery: A Case Report

Cho I

The spleen is an organ located in the upper left portion of the abdomen. Wandering spleen is defined as the location of the spleen is the shift to other parts...
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Real-life ruxolitinib experience in intermediate-risk myelofibrosis

Arikan F, Toptas T, Atagunduz IK, Ercan T, Oruc O, Yilmaz F, Tuglular T

Background In this retrospective cohort of patients with primary, post-polycythemia vera, or post-essential thrombocythemia myelofibrosis, 57 patients with MF who received ruxolitinib for MF-related symptoms or symptomatic splenomegaly were evaluated. Methods The median...
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Liver-to-Spleen Volume Ratio Automatically Measured on CT Predicts Decompensation in Patients with B Viral Compensated Cirrhosis

Kwon JH, Lee SS, Yoon JS, Suk HI, Sung YS, Kim HS, Lee Cm, Kim KM, Lee SJ, Kim SY

Objective: Although the liver-to-spleen volume ratio (LSVR) based on CT reflects portal hypertension, its prognostic role in cirrhotic patients has not been proven. We evaluated the utility of LSVR, automatically...
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Dietary glucosinolates inhibit splenic inflammation in high fat/cholesterol diet-fed C57BL/6 mice

Gu H, Gwon MH, Kim SM, Yun JM

BACKGROUND/OBJECTIVES: Obesity is associated with chronic inflammation. The spleen is the largest organ of the lymphatic system and has an important role in immunity. Obesity-induced inflammatory responses are triggered by Toll-like...
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Liver Function Analyses and Spleen Histology Assessment Following the Co-administration of Cisplatin and Methanolic Extract of Portulaca Oleracea in Wistar Rats: An Experimental Study

Okafor IA, Nnamah US, Nnaka J

This study investigated the biochemical and histological changes associated with the co-administration of cisplatin and methanolic extract of Portulaca Oleracea (MEPO) in adult Wistar rats. Twenty-four (24) adult female Wistar...
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Deep Learning Algorithm for Automated Segmentationand Volume Measurement of the Liver and Spleen UsingPortal Venous Phase Computed Tomography Images

Ahn Y, Yoon JS, Lee SS, Suk HI, Son JH, Sung YS, Lee Y, Kang BK, Kim HS

Objective: Measurement of the liver and spleen volumes has clinical implications. Although computed tomography (CT)volumetry is considered to be the most reliable noninvasive method for liver and spleen volume measurement,...
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Splenic myxoid liposarcoma in a dog

Go DM, Woo SH, Cheon D, Kim J, Oh YI, Kim DY

A 7-year-old Maltese was presented to a veterinary clinic for a history of anorexia, soft feces, and anemia. During abdominal sonography and computed tomography imaging, splenic mass was suspected. Laparotomy...
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Anti-colonic Inflammation by Black Raspberries through Regulating Toll-like Receptor-4 Signaling in Interlukin-10 Knockout Mice

Huang YW, Echeveste CE, Oshima K, Zhang J, Yearsley M, Yu J, Wang LS

Ulcerative colitis (UC) is a chronic inflammatory disease of the colon, with a steadily rising prevalence in Western and newly industrialized countries. UC patients have a cancer incidence as high...
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Two cases of splenic infarction due to torsion of wandering spleen requiring laparoscopic splenectomy in adolescent girls

Kim SH, Cho YH, Kim HY

Wandering spleen is a rare condition in which the spleen is not found in its usual location or presentation. Its vascular pedicle can be twisted easily, and compromised vasculature of...
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Advantages of Splenic Hilar Lymph Node Dissection in Proximal Gastric Cancer Surgery

Guner A, Hyung WJ

Gastrectomy with lymph node dissection remains the gold standard for curative treatment of gastric cancer. Dissection of splenic hilar lymph nodes has been included as a part of D2 lymph...
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Malignant Transformation of an Epidermoid Cyst in an Intrapancreatic Accessory Spleen: A Case Report

Wang J, Kang WJ, Cho H

A 33-year-old man was evaluated because of an incidentally found cyst in the pancreatic tail, which was first seen 6 years ago. The cyst was a unilocular cystic mass, 13.0...
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Spleen Scan for 68Ga-DOTATOC PET-Positive Pancreatic Tail Lesion: Differential Diagnosis of Neuroendocrine Tumor from Accessory Spleen

Ryoo HG, Choi H, Cheon GJ

68Ga-DOTATOC PET/CT is widely used as a functional imaging technique in the detection and characterization of neuroendocrine tumors (NETs). Pancreatic NET and intrapancreatic accessory spleen (IPAS) have similar radiologic characteristics...
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Subcapsular Splenic Hemorrhage in Vivax Malaria

Im JH, Chung MH, Durey A, Lee JS, Kim TS, Kwon HY, Baek JH

In malaria, splenic rupture is a serious complication potentially leading to death. Subcapsular hemorrhage of spleen is thought to be an impending sign of splenic rupture; however, the characteristics of...
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Modulatory action of enrofloxacin in lipopolysaccharide-induced hyper-activated mouse spleen cells

Ko HJ, Joo HG

Enrofloxacin, a fluoroquinolone, is a broad-spectrum antibiotic widely used in veterinary medicine that inhibits the action of bacterial DNA gyrase, resulting in anti-bacterial effects. This study was performed to examine...
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Spleen Preservation in Laparoscopic Distal Pancreatectomy for Solid Pseudopapillary Neoplasm is Oncologically Safe

Won Y, Yoon YS, Han HS, Cho JY, Choi Y, Hyun IG, Kim KH

PURPOSE: Laparoscopic distal pancreatectomy (LDP) has been widely performed for solid pseudopapillary neoplasm (SPN) involving the body or tail of the pancreas. However, it has not been established whether spleen...
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