Korean J Infect Dis.  2001 Oct;33(5):346-349.

A Case of Septic Portal Vein Thrombophlebitis: Presenting with Fever of Unknown Origin

Affiliations
  • 1Department of Internal Medicine, Chonnam National University, Medical School, Gwangju, Korea.
  • 2Department of Clinical Pathology, Chonnam National University, Medical School, Gwangju, Korea.

Abstract

Pylephlebitis is defined as an inflammation of the portal system, which is a rare but dreaded complication of intra-abdominal inflammatory processes. In the past it was observed as a sequela of neglected or complicated appendicitis. With earlier diagnosis, modern surgical technique and antibiotics, the incidence has declined even further. In addition, thrombosis in portal system (pylethrombosis) can complicate the pylephlebitis, followed by obstruction of the portal system, leading to portal hypertension in the late stage. Proper recognition of early thrombosis and an accompanying intra-abdominal inflammatory process should arouse the suspicion of septic thrombophlebitis and lead to the early institution of adequate therapy to prevent the almost universally fatal outcome. We report the case of woman who had pylephlebitis and presented with fever of unknown origin, probably associated with acute appendicitis.

Keyword

Fever of unknown origin; Pylephlebitis; Pylethrombosis; Appendicitis

MeSH Terms

Anti-Bacterial Agents
Appendicitis
Diagnosis
Fatal Outcome
Female
Fever of Unknown Origin*
Fever*
Humans
Hypertension, Portal
Incidence
Inflammation
Portal System
Portal Vein*
Thrombophlebitis*
Thrombosis
Anti-Bacterial Agents
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