J Rhinol.  2014 May;21(1):59-62. 10.0000/jr.2014.21.1.59.

A Case of Optic Neuropathy Secondary to Sphenoid Sinus Aspergillosis

• Jung SC
• Oh HJ
• Do NY
• Lee JE

• KMID: 2146676
• DOI: http://doi.org/10.0000/jr.2014.21.1.59

Abstract

Orbital complication of an isolated sphenoid sinus lesion is rare. We recently experienced one case of optic neuropathy secondary to sphenoid sinus Aspergillosis. The patient presented with a headache and diplopia. Imaging and histology showed a sphenoid sinus lesion, andthe patientunderwent endoscopic sinus surgery. Because of the disease progression after the surgery,the patient was administered an anti-fungal agent underclinical suspicion ofan invasive fungal sinusitis infection before receiving histologic confirmation of tissue invasion by fungal hyphae. The disease stabilized in three months by using approximately one month of anti-fungal agent. The type of treatment required for sphenoid sinus lesions depends on the extent of the disease upon initial examination as well ason the rapidity of diseaseprogression.

Keyword

Sphenoid Sinus; Aspergillosis; Optic Neuropathy

MeSH Terms

Aspergillosis*
Diplopia
Disease Progression
Headache
Humans
Hyphae
Optic Nerve Diseases*
Orbit
Sinusitis
Sphenoid Sinus*