Korean J Dermatol.  2000 Dec;38(12):1656-1659.

A Case of Necrobiosis Lipoidica with Prominent Cholesterol Cleft

• Jang HC
• Jung BC
• Kim SW

Abstract

We report an unusual case of necrobiosis lipoidica with prominent cholesterol clefts in a 36-year-old man who had developed multiple, 0.5~5cm in diameter, round to oval-shaped erythematous plaques on both shins for over 3 years. Laboratory findings showed the following; cholesterol, 250mg/dl; triglyceride, 208mg/dl; blood sugar level fasting/2-h postprandial, 101/92mg/dl; and other findings were within normal limits or negative. There was no paraproteinemia. The biopsy specimen showed various lymphohistiocytic granuloma with many giants cell in the mid and deep dermis, and septal fibrosis in the subcutaneous tissue. There were also extensive areas of necrobiosis with prominent cholesterol clefts mimicking necrobiotic xanthogranuloma.

Keyword

Necrobiosis lipoidica; Cholesterol clefts

MeSH Terms

Adult
Biopsy
Blood Glucose
Cholesterol*
Dermis
Fibrosis
Granuloma
Humans
Necrobiosis Lipoidica*
Necrobiotic Disorders*
Necrobiotic Xanthogranuloma
Paraproteinemias
Subcutaneous Tissue
Triglycerides
Blood Glucose
Cholesterol