Korean J Dermatol.  2011 Jan;49(1):62-67.

Three Cases of Churg-Strauss Syndrome Diagnosed after Presence of Cutaneous Manifestation

• Kim TW
• Song M
• Park HJ
• Kim HS
• Kim SH
• Ko HC
• Kim BS
• Kim MB
• Kwon KS

Abstract

Churg-Strauss syndrome (CSS) is an uncommon disorder that is characterized by asthma or allergic rhinitis, fever, systemic vasculitis, extravascular granulomas and hypereosinophilia. Cutaneous manifestations of CSS are one of the most common extra-pulmonary findings, and they occur in approximately 60% of the cases. Other manifestations include pulmonary infiltrates and heart, kidney, gastrointestinal tract, peripheral and central nervous system involvement and the patients also complain of systemic symptoms, including malaise, fever, myalgia and weight loss. The diagnosis of CSS is difficult because the manifestations vary with the disease stage and delayed treatment can lead to fatal major organ damage. We report here on 3 cases of CSS that were first diagnosed by the dermatologic department and with consultation from other departments. So, we want to remind dermatologists that if the patients of asthma or other allergic diseases have purpuric skin lesion, then CSS should be included in the differential diagnosis.

Keyword

Churg-Strauss syndrome; Vasculitis

MeSH Terms

Asthma
Central Nervous System
Churg-Strauss Syndrome
Diagnosis, Differential
Fever
Gastrointestinal Tract
Granuloma
Heart
Humans
Kidney
Rhinitis
Rhinitis, Allergic, Perennial
Skin
Systemic Vasculitis
Vasculitis
Weight Loss