Korean J Anesthesiol.  1993 Jun;26(3):576-580. 10.4097/kjae.1993.26.3.576.

A Case Report of Malignant Hyperthermia during Anesthesia

• Hwang JH
• Lee YG
• Woo S
• Cho KH

• KMID: 2145933
• DOI: http://doi.org/10.4097/kjae.1993.26.3.576

Abstract

Malignant hyperthermia is a potentially fatal hypermetabolic syndrome characterised by hyperpyrexia and skeletal muscle rigidity. It can be induced by all of the currently used inhalation anesthetics or by injection of succinylcholine. A case of malignant hyperthermia was experienced which developed 80 minute after induction of general anesthesia with thiopental sodium, suecinylcholine, halothane, N2O and O2. One and half hours after induction, arrhythmia developed and was followed by unstable blood pressure, hyperpyrexia and muscle rigidity. Anesthesia was terminated and vigorous emergency treatment and dantrolene were administered. The patient recovered normal body temperature and consciousness, but expired about 4 days after induction because of late complication including disseminated intravascular coaggulation. The etiologic factor, clinieal feature, treatment and prevention of Malignant hyperthermia are discussed.

Keyword

Malignant hyperthermia; Halothane; Succinylcholine; Dantrolene

MeSH Terms

Anesthesia*
Anesthesia, General
Anesthetics, Inhalation
Arrhythmias, Cardiac
Blood Pressure
Body Temperature
Consciousness
Dantrolene
Emergency Treatment
Halothane
Humans
Malignant Hyperthermia*
Muscle Rigidity
Muscle, Skeletal
Succinylcholine
Thiopental
Anesthetics, Inhalation
Dantrolene
Halothane
Succinylcholine
Thiopental