Korean J Anesthesiol.  1993 Jun;26(3):506-511. 10.4097/kjae.1993.26.3.506.

Erythrocyte 2,3-DPG and ATP Concentration in Intraoperative Salvaged Blood and CPD Stored Blood

Affiliations
  • 1Department of Anesthesiology, Natonal Medical Center, Seoul, Korea.

Abstract

The purpose of this study is to compare the quality of intraoperative salvaged blood with that of Citrate Phosphate Dextrose(CPD) stored blood in 32 patients having cardiac surgery involving cardiopulmonary bypass. 20 patients in the control group received one week cild CPD stored blood and 12 patients received autologous intraoperative salvaged blood which prepared and processed with the Hemonetics Cell Saver Plus autotransfusion device. 1) Salvaged blood had a higher hemoglobin concentration(l7.6 vs 13.1 g/dl, P<0.005), a higher 2.3-diphosphoglycerate concentration(3.1 vs 0.6 mmol/L, P<0.005), higher pH(7.6 vs 6.8, P<0.005) than CPD stored blood group. Salvaged blood had a lower ATP concentration was(47.7 vs 67.7 pmol/dl, P<0.005) than stored blood group. 2) Platelet count was l3.4 X 10(9)/L and WBC count was 5.09 X 10(9)/L in salvaged blood. 3) Salvaged blood volume was 1411+/-487.9 ml(range 580 to 2325 ml). Intraoperative salvaged blood had a superior oxygen carrying and delivery capacity, but modification of washing is required to lessen the platelet and white blood cell count in the salvaged blood.

Keyword

Transfusion; 2, 3-DPG; ATP; autotransfusion

MeSH Terms

2,3-Diphosphoglycerate*
Adenosine Triphosphate*
Blood Platelets
Blood Transfusion, Autologous
Blood Volume
Cardiopulmonary Bypass
Citric Acid
Erythrocytes*
Humans
Leukocyte Count
Oxygen
Platelet Count
Thoracic Surgery
2,3-Diphosphoglycerate
Adenosine Triphosphate
Citric Acid
Oxygen
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