Korean Circ J.  2010 Apr;40(4):197-200. 10.4070/kcj.2010.40.4.197.

Acute Myocardial Infarction due to Polyarteritis Nodosa in a Young Female Patient

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. ygko@yuhs.ac
  • 2Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 3Division of Cardiology, Department of Internal Medicine, College of Medicine, Soonchunhyang University, Seoul, Korea.

Abstract

Coronary artery aneurysms are uncommon, are usually associated with atherosclerosis, and rarely involve all three major coronary arteries. The present report describes a rare case of a young female patient presenting with acute myocardial infarction (AMI). Coronary angiography revealed multiple severe aneurysmal and stenotic changes. Based on clinical feature and angiographic findings, it was strongly suspected that the patient had polyarteritis nodosa (PAN) complicated by AMI. The patient was treated with standard cardiac medications and immunosuppressive agents and has remained stable without further complications during a follow-up period of 6 months.

Keyword

Coronary aneurysm; Myocardial infarction; Polyarteritis nodosa; Vasculitis

MeSH Terms

Aneurysm
Atherosclerosis
Coronary Aneurysm
Coronary Angiography
Coronary Vessels
Female
Follow-Up Studies
Humans
Immunosuppressive Agents
Myocardial Infarction
Polyarteritis Nodosa
Vasculitis
Immunosuppressive Agents

Figure

  • Fig. 1 Coronary angiography. A: anteroposterior caudal view shows multiple aneurysmal changes of the left main and the left anterior descending artery with total occlusion of the left circumflex artery. B: left anterior oblique cranial view shows a huge aneurysmal dilatation of the proximal part and critical stenotic lesions of the posterolateral branch in the right coronary artery.

  • Fig. 2 Brain magnetic resonance angiography. A small aneurysm arose from the left thyrocervical trunk (arrow).

  • Fig. 3 Computed tomographic angiography. A small aneurysm was seen at the posterior division of the left renal artery (arrow).


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