J Korean Soc Neonatol.
2005 Nov;12(2):227-232.
Candida albicans Brain Abscesses in Extremely Low Birth Weight Infant Treated with Amphotericin B, Flucytosine, and Fluconazole
- Affiliations
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- 1Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. arkim@amc.seoul.kr
- 2Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Abstract
- Systemic candidiasis in premature infants often involves the central nervous system (CNS) but only a few reported cases of candidiasis involving the brain parenchyma were found in a recent search of the literature and there is no uniformly accepted approach for treatment of CNS Candida infection in neonates. We report a case of extremely low birth weight infant who had candiduria and Candida meningitis with multiple abscesses formation in brain parenchyma who was successfully treated with long term amphotericin B, flucytosine, and fluconazole therapy without surgical drainage.
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