J Korean Soc Magn Reson Med.  2013 Dec;17(4):316-320. 10.13104/jksmrm.2013.17.4.316.

Imaging Findings of Metastatic Breast Malignant Fibrous Histiocytoma: A Case Report

Affiliations
  • 1Department of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea. lionmain@catholic.ac.kr
  • 2Department of Pathology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.

Abstract

Malignant fibrous histiocytoma (MFH) of the breast is extremely rare and most of the previous reports were focused on the clinicopathological features of breast MFH, so analysis of its imaging findings have been limited. We report a case of MFH involving left breast and left axilla, metastasized from known MFH of left forearm, with focusing on imaging findings based on radiologic evaluation of the breast including mammography, ultrasound and breast MRI.

Keyword

Malignant fibrous histiocytoma; Breast; Magnetic resonance image

MeSH Terms

Axilla
Breast*
Forearm
Histiocytoma, Malignant Fibrous*
Magnetic Resonance Imaging
Ultrasonography, Mammary

Figure

  • Fig. 1 A 79-year-old woman with multiple metastatic MFH in left axilla and left breast. a. Initial mammography shows huge high density, relatively circumscribed mass in left axilla at mediolateral oblique view (upper panel, arrow) and several small ill-defined masses in left breast at craniocaudal view (lower panel, arrow) with diffuse skin thickening (arrow head) and trabecular thickening, categorized BI-RADS C0. b. On ultrasound, multiple circumscribed oval to round, heterogeneous hypoechoic or complex echoic solid masses with posterior acoustic enhancement and increased vascularity are noted in left axilla and left breast. Echogenic nodular skin involvement is also noted. c. On breast MRI, partly included left axillary enhancing mass shows heterogeneous T2 high, T1 iso-signal intensity. Multiple small enhancing masses, T1 and T2 iso-signal intensity to fibroglandular tissue, are noted in left breast with diffuse breast edema and some of them show diffusion restriction. d. Pathologic examination of the left breast mass shows spindle cell proliferation with myxoid change (H & E, ×200).


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