Korean J Cytopathol.  2008 Sep;19(2):178-182. 10.3338/kjc.2008.19.2.178.

Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology in the Diagnosis of a Gastrointestinal Stromal Tumor of the Stomach: A Case Report

Affiliations
  • 1Department of Pathology, College of Medicine, Inha University, Incheon, Korea. jmkpath@inha.ac.kr
  • 2Department of Gastroenterology, College of Medicine, Inha University, Incheon, Korea.

Abstract

We report here a case of a gastrointestinal stromal tumor (GIST) in the stomach that was diagnosed by endoscopic ultrasound-guided fine needle aspiration cytology (EUS-FNA). A 67 year old male patient underwent regular check-ups for five years due to the presence of a submucosal tumor that was found in the fundus of the stomach incidentally. EUS-FNA was performed to evaluate the tumor, which had increased in size from 1cm to 2.8cm. A cytologic smear revealed cohesive sheets or clusters of spindle cells with elongated nuclei. Immunohistochemical staining revealed a strong positive reaction for c-kit and CD34, without any reaction for smooth muscle actin and Ki-67. Therefore, a diagnosis of GIST was made.

Keyword

Gastrointestinal stromal tumor; Endoscopy; Ultrasound-guided fine needle aspiration cytology; Immunohistochemistry

MeSH Terms

Actins
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Endoscopy
Gastrointestinal Stromal Tumors
Humans
Immunohistochemistry
Male
Muscle, Smooth
Stomach
Actins
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