Korean J Hematol.  2002 Nov;37(4):307-311.

Combination Chemotherapy to Hodgkin's Disease in a Pregnant Patient

• Song EK
• Kwak JY
• Lee SO
• Yim CY

Abstract

Coincident Hodgkin's disease and pregnancy is rare and optimal management requires special consideration because usual treatment modalities are associated with significant risk to the developing fetus. We have experienced a 20 weeks pregnant woman with Hodgkin's disease. Combination chemotherapy with ABV (Adriamycin, Bleomycin, Vinblastine) 3 cycles were given during 2nd and 3rd trimester. She was delivered of a baby the 40 weeks of pregnancy without any problem. After delivery, she received additional 3 cycles of combination chemotherapy with ABVD (Adriamycin, Bleomycin, Vinblastine, Dacarbazine). Then, radiation treatment with Mantle technique, total 3,600cGy was performed. Finally, she reached the complete remission. After 12 months from the end of treatment, there was no evidence of recurrence and the baby are developing without any anomaly.

Keyword

Hodgkin's disease; Pregnancy; ABVD

MeSH Terms

Bleomycin
Drug Therapy, Combination*
Female
Fetus
Hodgkin Disease*
Humans
Pregnancy
Pregnant Women
Recurrence
Vinblastine
Bleomycin
Vinblastine