Korean J Obes.  2013 Sep;22(3):148-154.

Relationship Between Obesity Indices and Cardiovascular Risk Score in Korean Type 2 Diabetes Patients

Affiliations
  • 1Department of Internal Medicine, Jeju National University Hospital, Korea. okdom@medimail.co.kr
  • 2Department of Internal Medicine, Jeju National University School of Medicine, Korea.
  • 3Department of Nephrology, Asan Medical Cencer, Korea.
  • 4Department of Endocrinology & Metabolism, Wonkwang University Hospital, Korea.
  • 5Department of Endocrinology & Metabolism, Konyang University Hospital, Korea.
  • 6Department of Endocrinology & Metabolism, Gachon University Gil Medical Center, Korea.

Abstract

BACKGROUND
We aimed to determine which index of obesity is the best discriminator of cardiovascular (CV) risk in Korean type 2 diabetes (T2DM) patients.
METHODS
This is a cross-sectional study involving 1,111 T2DM patients from two university hospitals. We measured body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), and biochemical CV risk factors in all subjects. The 10-year coronary heart disease risk was calculated with the Framingham Risk Score.
RESULTS
BMI showed significant correlation with SBP (systolic blood pressure), DBP (diastolic blood pressure), TC (total cholesterol), TG (triglyceride), HDL-C, and LDL-C. WC showed significant correlation to SBP, DBP, homocysteine, TG and HDL-C. WHR was significantly associated with SBP, DBP, TG, HDL and microalbuminuria. WHtR was significantly correlated to SBP, TG, HDL-C and LDL-C. WC (P < or = 0.001, P for trend < or = 0.001), WHR (P = 0.002, P for trend < or = 0.001) and WHtR (P = 0.001, P for trend < or = 0.001), except for BMI (P = 0.628, P for trend = 0.258), showed significant differences according to increasing quintiles of Framingham Risk Score.
CONCLUSION
WC, WHR and WHtR were more closely related to CV risk score than BMI in Korean T2DM patients.

Keyword

Type 2 diabetes; Body mass index; Waist circumference; Waist-to-hip ratio; Waist-to-height ratio; Framingham risk score

MeSH Terms

Body Mass Index
Coronary Disease
Cross-Sectional Studies
Homocysteine
Hospitals, University
Humans
Obesity*
Risk Factors
Waist Circumference
Waist-Hip Ratio
Homocysteine
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