Hanyang Med Rev.
2009 May;29(2):148-167.
Pharmacologic Treatment Strategies of Type 2 Diabetes
- Affiliations
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- 1Department of Internal Medicine, School of Medicine, Hanyang University, Seoul, Korea. ahnyh@hanyang.ac.kr
Abstract
- Type 2 diabetes has become epidemic in the past several decades owing to advancing age, a substantially increased prevalence of obesity and decreased physical activities etc. Achieving & maintaning glycemic level as close to the nondiabetic range as possible through intensive diabetes therapy has been demonstrated to have a powerful beneficial effect on diabetesspecific microvascular complications in type 1 & type 2 diabetes. However, diabetes is associated with a reduced lifespan, largely as a consequence of cardiovascular disease. Unlike type 1 diabetes, current studies have failed to demonstrate a beneficial effect of intensive diabetes therapy on cardiovascular disease in type 2 diabetes. Accordingly, special consideration may now need to be given to high-risk patients with multiple risk factors & heart disease. Therefore, comprehensive approach to the treatment of type 2 diabetes that include the treatment of all of the coexisting risk factors for cardiovascular disease has to be implemented and achieved
