J Korean Med Assoc.  2004 May;47(5):441-445. 10.5124/jkma.2004.47.5.441.

Chemoprevention

• Cheon J

• KMID: 2137879
• DOI: http://doi.org/10.5124/jkma.2004.47.5.441

Abstract

Despite advance in detection and management of prostate cancer, this disease remains a major cause of morbidity and mortality in men. Increasing attention has focused on the role of chemoprevention for prostate cancer, ie the administration of agents that inhibit one or more steps in the natural history of prostate carcinogenesis. Chemoprevention of prostate cancer is currently being tested in a wide range of clinical trials, and have focused on the role of dietary factors, vitamins and trace elements in prostate cancer. These studies have the potential to fundamentally alter the current approach to prostate cancer management. The current status of clinical trials investigating the use of interventions designed to reduce the risk of prostate cancer is reviewed.

Keyword

Prostate cancer; Chemoprevention

MeSH Terms

Carcinogenesis
Chemoprevention*
Humans
Male
Mortality
Natural History
Prostate
Prostatic Neoplasms
Trace Elements
Vitamins
Trace Elements
Vitamins