- Malignant transformation in a Breast Adenomyoepithelioma Caused by Amplification of c-MYC: A Common pathway to Cancer in a Rare Entity
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Febres-Aldana CA, Mejia-Mejia O, Krishnamurthy K, Mesko T, Poppiti R
- KMID: 2470885
- J Breast Cancer.
- 2020 Feb;23(1):93-99.
- doi: 10.4048/jbc.2020.23.e2
Breast adenomyoepitheliomas are composed of a biphasic proliferation of myoepithelial cells around small epithelial-lined spaces. Due to the rarity of adenomyoepitheliomas, the molecular data describing them are limited. Adenomyoepitheliomas are... -
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- Expression of Histo-blood Group Antigens in Tumor and Adjacent Normal Breast Tissues as Prognostic Markers of Breast Carcinoma
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Zouine S, Marnissi F, Otmani N, Bennani Othmani M, Zaid N, Kojok K, Zaid Y, Tahiri Jouti N, Habti N
- KMID: 2470883
- J Breast Cancer.
- 2020 Feb;23(1):69-79.
- doi: 10.4048/jbc.2020.23.e13
PURPOSE: Aberrant glycosylation of the histo-blood group antigens (including the angina bullosa haemorrhagica [ABH]) is often observed during malignant transformation in most types of carcinomas. Data concerning their ethnic distributions... -
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- Cellular Senescence in Arterial Diseases
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Shimizu I, Minamino T
- KMID: 2470802
- J Lipid Atheroscler.
- 2020 Jan;9(1):79-91.
- doi: 10.12997/jla.2020.9.1.79
Cell-proliferation potency is limited, as cells cannot proceed through the cell cycle continually. Instead, they eventually show an irreversible arrest of proliferation, commonly referred to as cellular senescence. Following the... -
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- Chimeric Antigen Receptor T Cell Therapy: A Novel Modality for Immune Modulation
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Yoon S, Eom GH
- KMID: 2468140
- Chonnam Med J.
- 2020 Jan;56(1):6-11.
- doi: 10.4068/cmj.2020.56.1.6
Cancer remains a leading cause of death, despite multimodal treatment approaches. Even in patients with a healthy immune response, cancer cells can escape the immune system during tumorigenesis. Cancer cells... -
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- Scavenger Receptor Class A to E Involved in Various Cancers
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Ryu S, Howland A, Song B, Youn C, Song PI
- KMID: 2468139
- Chonnam Med J.
- 2020 Jan;56(1):1-5.
- doi: 10.4068/cmj.2020.56.1.1
Scavenger receptors typically bind to multiple ligands on a cell surface, including endogenous and modified host-derived molecules and microbial pathogens. They promote the elimination of degraded or harmful substances such... -
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- Curcumin Inhibits the Proliferation, Migration, Invasion, and Apoptosis of Diffuse Large B-Cell Lymphoma Cell Line by Regulating MiR-21/VHL Axis
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Chen L, Zhan CZ, Wang T, You H, Yao R
- KMID: 2466332
- Yonsei Med J.
- 2020 Jan;61(1):20-29.
- doi: 10.3349/ymj.2020.61.1.20
PURPOSE: Curcumin exerts its anti-cancer effects, partly by targeting special microRNAs, in human cancers. MiR-21 is a key oncomir in carcinogenesis of multiple human cancers. Here, we aimed to further... -
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- Long non-coding RNA linc00152 acting as a promising oncogene in cancer progression
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Seo D, Kim D, Kim W
- KMID: 2468862
- Genomics Inform.
- 2019 Dec;17(4):e36.
- doi: 10.5808/GI.2019.17.4.e36
The incidence and mortality rate of cancer continues to gradually increase, although considerable research effort has been directed at elucidating the molecular mechanisms underlying biomarkers responsible for tumorigenesis. Accumulated evidence... -
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- Circular RNAs Regulate Cancer Onset and Progression via Wnt/β-Catenin Signaling Pathway
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Li YF, Zhang J, Yu L
- KMID: 2463790
- Yonsei Med J.
- 2019 Dec;60(12):1117-1128.
- doi: 10.3349/ymj.2019.60.12.1117
Cancer remains to be a major challenge for public health providers, and is the second leading cause of death worldwide. Therefore, it is imperative to explore the mechanisms underlying cancer... -
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- Rab25 Deficiency Perturbs Epidermal Differentiation and Skin Barrier Function in Mice
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Jeong H, Lim KM, Goldenring JR, Nam KT
- KMID: 2462882
- Biomol Ther.
- 2019 Nov;27(6):553-561.
- doi: 10.4062/biomolther.2019.125
Rab25, a member of the Rab11 small GTPase family, is central to achieving cellular polarity in epithelial tissues. Rab25 is highly expressed in epithelial cells of various tissues including breast,... -
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- Relationship between the precursors of high grade serous ovarian cancer and patient characteristics: decreased incidence of the p53 signature in pregnant women
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Ida T, Fujiwara H, Kiriu T, Taniguchi , Kohyama A
- KMID: 2458901
- J Gynecol Oncol.
- 2019 Nov;30(6):e96.
- doi: 10.3802/jgo.2019.30.e96
OBJECTIVE: To investigate the relationship between the precursors of high grade serous ovarian cancer (HGSOC) and the characteristics of patients with a low HGSOC risk in terms of the effects... -
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- Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis
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Li N, Piao J, Wang X, Kim KY, Bae JY, Ren X, Lin Z
- KMID: 2460613
- Cancer Res Treat.
- 2019 Oct;51(4):1653-1665.
- doi: 10.4143/crt.2018.544
PURPOSE: This study was aimed to investigate the role of poly(A)-binding protein-interacting protein 1 (Paip1) in cervical carcinogenesis. MATERIALS AND METHODS: The expression of Paip1 in normal cervical epithelial tissues and... -
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- Sonic Hedgehog Pathway as the Prognostic Marker in Patients with Extensive Stage Small Cell Lung Cancer
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Lim S, Lim SM, Kim MJ, Park SY, Kim JH
- KMID: 2459142
- Yonsei Med J.
- 2019 Oct;60(10):898-904.
- doi: 10.3349/ymj.2019.60.10.898
PURPOSE: Sonic hedgehog (Shh) signaling pathway is known to play a crucial role in carcinogenesis in various malignancies, including lung cancer regarding tumorigenesis, angiogenesis, and cellular differentiation. The aim of... -
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- Epidemiology of and Risk Factors for Esophageal Cancer in Korea
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Jung HK
- KMID: 2469326
- Korean J Helicobacter Up Gastrointest Res.
- 2019 Sep;19(3):145-148.
- doi: 10.7704/kjhugr.2019.19.3.145
Esophageal cancer is an aggressive malignant tumor with a poor prognosis because of its typically advanced stage at diagnosis and treatment-related morbidity and mortality. Of the two major subtypes, esophageal... -
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- A Putative Adverse Outcome Pathway Relevant to Carcinogenicity Induced by Sulfuric Acid in Strong Inorganic Acid Mists
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Yang JH, Koedrith P, Kang DS, Kee NK, Jung JH, Lee CM, Ahn YS, Seo YR
- KMID: 2468795
- J Cancer Prev.
- 2019 Sep;24(3):139-145.
- doi: 10.15430/JCP.2019.24.3.139
Based on epidemiological studies, an International Agency for Research on Cancer Working Group determined that strong inorganic acid mists containing sulfuric acid are carcinogenic to human even though, sulfuric acid,... -
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- Immunohistochemical Study of Fas/Fas-ligand and Cadherin Expression in Basal Cell Carcinoma in Sun-Exposed and Sun-Protected Areas
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Kim JH, Suh HS, Choi YS
- KMID: 2465949
- Korean J Dermatol.
- 2019 Sep;57(8):425-432.
BACKGROUND: UV radiation is the most important risk factor in the development of basal cell carcinoma (BCC). However, the association between tumorigenesis and the progression of BCC and UV exposure... -
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- Induction of cell deathin early developmental phase of zebrafish treated with diethylnitrosamine
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Kang JS
- KMID: 2463591
- J Biomed Transl Res.
- 2019 Sep;20(3):53-57.
- doi: 10.12729/jbtr.2019.20.3.053
The purpose of this study was to investigate diethylnitrosamine (DEN)-induced liver damage in zebrafish. Zebrafish larvae were divided into five groups after seventy-two hours fertilization: group 1 (G1) as control,... -
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- Identification of neoantigens derived from alternative splicing and RNA modification
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Park J, Chung YJ
- KMID: 2462037
- Genomics Inform.
- 2019 Sep;17(3):e23.
- doi: 10.5808/GI.2019.17.3.e23
The acquisition of somatic mutations is the most common event in cancer. Neoantigens expressed from genes with mutations acquired during carcinogenesis can be tumor-specific. Since the immune system recognizes tumor-specific... -
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- Clinicopathological Characterization and Prognostic Implication of SMAD4 Expression in Colorectal Carcinoma
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Yoo SY, Lee JA, Shin Y, Cho NY, Bae JM, Kang GH
- KMID: 2459577
- J Pathol Transl Med.
- 2019 Sep;53(5):289-297.
- doi: 10.4132/jptm.2019.06.07
BACKGROUND: SMAD family member 4 (SMAD4) has gained attention as a promising prognostic factor of colorectal cancer (CRC) as well as a key molecule to understand the tumorigenesis and progression... -
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- Biomarkers for Evaluating the Inflammation Status in Patients with Cancer
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Guner A, Kim HI
- KMID: 2458827
- J Gastric Cancer.
- 2019 Sep;19(3):254-277.
- doi: 10.5230/jgc.2019.19.e29
Inflammation can be a causative factor for carcinogenesis or can result from a consequence of cancer progression. Moreover, cancer therapeutic interventions can also induce an inflammatory response. Various inflammatory parameters... -
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- A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric Cancer
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Chung HW, Kim JJ, Choi JI, Lee HR, Lim JB
- KMID: 2452951
- Yonsei Med J.
- 2019 Aug;60(8):713-719.
- doi: 10.3349/ymj.2019.60.8.713
PURPOSE: We aimed to evaluate the clinical significance of a disintegrin and metalloproteinase 8 (ADAM 8) as a potential blood biomarker for gastric cancer (GC). MATERIALS AND METHODS: Blood ADAM 8... -
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