J Korean Acad Rehabil Med.
2001 Apr;25(2):330-335.
Mixed Quadriplegia with Lissencephaly and Dysmyelination
- Affiliations
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- 1Department of Rehabilitation Medicine, The Catholic University of Korea, School of Medicine.
Abstract
- Lissencephaly results from a neuromigrational arrest during first and second trimester of pregnancy and shows hypotonia, marked mental retardation and seizure as predominant features. Myelination is a perinatal process and co-occurence of migrational disorder with myelination disorder is rare. We report a 17-month-old male with mixed quadriplegia and mental retardation with type 1 lissencephaly and dysmyelination of cerebral white matter diagnosed by magnetic resonance imaging.
