Infect Chemother.
2005 Dec;37(6):350-354.
A Case Report on Cryptococcal Lymphadenitis in an Immunocompetent Adult Patient
- Affiliations
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- 1Division of Infectious Disease, Department of Internal Medicine, Korea University College of Medicine, Korea. heejinmd@korea.ac.kr
- 2Department of Pathology, Korea University College of Medicine, Korea.
- 3Department of Internal Medicine, Sam An Yang Hospital, Seoul, Korea.
Abstract
- Cryptococcus neoformans is an organism that mainly causes opportunistic infection in immunocompromised patients. It can also cause various infections in immunocompetent patients, but cryptococcal lymphadenitis is rare. We have experienced a case of cryptococcal lymphadenitis in an immunocompetent adult patient who presented with cervical lymphadenopathy and fever that did not subside for 3 weeks. Neck and chest CT scan showed multiple lymph node enlargements with central low density and peripheral enhancement on both hilar, mediastinal, and right supraclavicular areas. Cryptococcus lymphadenitis was diagnosed by tissue biopsy, PAS and GMS stain, and culture. This case emphasizes that when an immunocompetent patient presents with lymphadenopathy, cryptococcal lymphadenitis should always be considered in the differential diagnosis.
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