Clin Pediatr Hematol Oncol.
2006 Oct;13(2):238-242.
A Case of Pulmonary Blastoma with Rhabdomyoblastic Differentiation
- Affiliations
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- 1Department of Pediatrics, Gyeongsang National University College of Medicine, Jinju, Korea. pedneu@gsnu.ac.kr
Abstract
- Pulmonary blastoma is a rare primary malignant neoplasm of lung with poor prognosis in children. Histologically, it is composed of epithelial and mesenchymal element: the latter may show various pattern of differentiation toward mature tissue, such as cartilage, smooth muscle, and bone. Rhabdomyoblastic differentiation in pulmonary blastoma is quite rare. In the literature, only eight cases have been reported including a Korean patient. Complete surgical removal is always required for the treatment and chemotherapy and radiotherapy are needed as adjuvant therapy. We report a case of pulmonary blastoma with rhabdomyoblastic differentiation treated with surgical removal, chemotherapy (vincristine, actinomycin D, cyclophosphamide, adriamycin) and radiotherapy.
