Allergy Asthma Immunol Res.  2010 Jul;2(3):172-176. 10.4168/aair.2010.2.3.172.

Evolution of Asthma Concept and Effect of Current Asthma Management Guidelines

Affiliations
  • 1Dokkyo Medical University, Tochigi, Japan. makinosoh@ac.auonenet.jp
  • 2Dokkyo Medical University, Koshigaya Hospital, Saitama, Japan.

Abstract

Concept of asthma has changed from symptom-complex or airway hypersensitivity to airway inflammation and airway remodeling. Based on this concept asthma management guidelines (JGL) has been developed in Japan. Death from asthma has decreased drastically since the publication of the guidelines, although it is still high in elderly population. Further works are expected for "zero-death" from asthma and for tighter control of airway inflammation and resultant airway remodeling.

Keyword

Asthma; concept; guideline; airway remodeling

MeSH Terms

Aged
Airway Remodeling
Asthma
Humans
Hypersensitivity
Inflammation
Japan
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