Blood Res.  2015 Dec;50(4):262-264. 10.5045/br.2015.50.4.262.

Bilateral Parotid MALToma: a sure shot for radiation

Affiliations
  • 1Department of Radiotherapy, Christian Medical College and Hospital, Ludhiana, India. kalrababusha@gmail.com
  • 2Department of Clinical Hematology and Hemat Oncology, Christian Medical College and Hospital, Ludhiana, India.
  • 3Department of Pathology, Christian Medical College and Hospital, Ludhiana, India.
  • 4Department of Radiology, Christian Medical College and Hospital, Ludhiana, India.

Abstract

No abstract available.


Figure

  • Fig. 1 (A) Left parotid swelling measuring 5.8×4.2×4 cm at initial diagnosis. (B) Complete clinical response after radiotherapy.

  • Fig. 2 Contrast enhanced T1- weighted axial and coronal magnetic resonance imaging showing a 5.8×4.2×4 cm lesion replacing the left parotid gland and a 3×2×2 cm lesion in the right parotid gland (A, C). T2-weighted axial and coronal images showing homogenously hyperintense lesions in both parotid glands (B, D).

  • Fig. 3 (A) Expanded pale looking marginal zone (arrows) surrounding a lymphoid follicle (LF), H&E ×100. (B) Marginal zone cells with round to slightly irregular nuclei and moderate amount of pale cytoplasm, H&E ×400. (C) to (F) Immunohistochemistry showing a CD20+, CD10-, CD23- and CD5-neoplastic lymphoid cells. DAB chromogen ×400.


Reference

1. Harris NL, Jaffe ES, Stein H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood. 1994; 84:1361–1392. PMID: 8068936.
2. Thieblemont C, Berger F, Dumontet C, et al. Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed. Blood. 2000; 95:802–806. PMID: 10648389.
Article
3. Balm AJ, Delaere P, Hilgers FJ, Somers R, Van Heerde P. Primary lymphoma of mucosa associated lymphoid tissue (MALT) in the parotid gland. Clin Otolaryngol Allied Sci. 1993; 18:528–532. PMID: 8877235.
Article
4. Mehle ME, Kraus DH, Wood BG, Tubbs R, Tucker HM, Lavertu P. Lymphoma of the parotid gland. Laryngoscope. 1993; 103:17–21. PMID: 8421414.
Article
5. Ciccone E, Truini M, Grossi CE. Lymphoid complement of the human salivary glands: function and pathology. Eur J Morphol. 1998; 36(Suppl):252–256. PMID: 9825932.
6. Diss TC, Wotherspoon AC, Speight P, Pan L, Isaacson PG. B-cell monoclonality, Epstein Barr virus, and t(14;18) in myoepithelial sialadenitis and low-grade B-cell MALT lymphoma of the parotid gland. Am J Surg Pathol. 1995; 19:531–536. PMID: 7726362.
7. Marioni G, Marchese-Ragona R, Marino F, et al. MALT-type lymphoma and Warthin's tumour presenting in the same parotid gland. Acta Otolaryngol. 2004; 124:318–323. PMID: 15141762.
Article
8. Rosenstiel DB, Carroll WR, Listinsky CM. MALT lymphoma presenting as a cystic salivary gland mass. Head Neck. 2001; 23:254–258. PMID: 11428457.
Article
9. Anacak Y, Miller RC, Constantinou N, et al. Primary mucosa-associated lymphoid tissue lymphoma of the salivary glands: a multicenter Rare Cancer Network study. Int J Radiat Oncol Biol Phys. 2012; 82:315–320. PMID: 21075560.
Article
10. Ferri C, Caracciolo F, Zignego AL, et al. Hepatitis C virus infection in patients with non-Hodgkin's lymphoma. Br J Haematol. 1994; 88:392–394. PMID: 7803287.
Article
11. Ando M, Matsuzaki M, Murofushi T. Mucosa-associated lymphoid tissue lymphoma presented as diffuse swelling of the parotid gland. Am J Otolaryngol. 2005; 26:285–288. PMID: 15991099.
Article
12. Perry C, Herishanu Y, Metzer U, et al. Diagnostic accuracy of PET/CT in patients with extranodal marginal zone MALT lymphoma. Eur J Haematol. 2007; 79:205–209. PMID: 17662066.
Article
13. Tsai HK, Li S, Ng AK, Silver B, Stevenson MA, Mauch PM. Role of radiation therapy in the treatment of stage I/II mucosa-associated lymphoid tissue lymphoma. Ann Oncol. 2007; 18:672–678. PMID: 17218489.
Article
14. Wenzel C, Fiebiger W, Dieckmann K, Formanek M, Chott A, Raderer M. Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue of the head and neck area: high rate of disease recurrence following local therapy. Cancer. 2003; 97:2236–2241. PMID: 12712477.
15. Zinzani PL, Magagnoli M, Ascani S, et al. Nongastrointestinal mucosa-associated lymphoid tissue (MALT) lymphomas: clinical and therapeutic features of 24 localized patients. Ann Oncol. 1997; 8:883–886. PMID: 9358939.
Article
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