J Korean Ophthalmol Soc.  2002 Mar;43(3):443-448.

Histological Progress Observation of Conjunctival MALToma

• Byon D
• Moon Y
• Kim J
• Kwak H

Abstract

PURPOSE: We report six cases of histologically diagnosed conjunctival MALT (mucosa-associated lymphoid tissue)oma. Presenting symptoms were eyelid swelling, foreign body sensation, lid mass, injection and itching sensation.
PATIENTS AND METHODS
Six patients with conjunctival MALToma were followed. Clinical progress and biopsy result were reviewed periodically.
RESULTS
The conjunctival MALToma seemed to be localized and slowly progressive. Although the conjunctival MALToma is known to be well responsive to radiotherapy, two of three patients who received radiotherapy revealed to have remnant lymphoma cells histologically in conjunctival biopsy. In addition, chemotherapy did not have curative effect in any of the patients.
CONCLUSIONS
Therefore, we are doubtful for the necessity of active treatment in MALTomas of the conjunctiva.

Keyword

Chronic conjunctivitis; Conjunctival MALToma; Low grade malignant lymphoma

MeSH Terms

Biopsy
Conjunctiva
Drug Therapy
Eyelids
Foreign Bodies
Humans
Lymphoma
Pruritus
Radiotherapy
Sensation