J Korean Ophthalmol Soc.  2007 Mar;48(3):460-464.

Conjunctival MALToma Patient with Intraocular Manifestation: A Case Report

• Suh MH
• Kim JH
• Yu HG

Abstract

PURPOSE: To report one case of unilateral intraocular involvement of the MALToma (Mucosa Associated Lymphoid Tissue Lymphoma) in the patient with bilateral conjunctival MALToma which was cured by radiation therapy 8 years ago.
METHODS
A 64 year old woman who was in remission status after radiation therapy of the bilateral conjunctival MALToma presented with vitreous opacity, inflammatory reaction in anterior chamber, iris posterior synechiae and keratic precipitate in her left eye. Visual acuity of her left eye decreased from 20/33 to 20/100. Pars planar vitrectomy and cytologic analysis of the vitreous sample were performed.
RESULTS
Cytologic analysis of the vitreous sample showed atypical lymphoid cells containing vacuolar nuclei which were stained positive at CD20 marker in the immunohistochemistry. So radiation therapy of the left eye was performed in the diagnosis of intraocular involvement of the MALToma.
CONCLUSIONS
If severe panuveitis occurs in the patient with radiation therapy of the conjunctival MALToma, intraocular involvement of the MALToma should be considered as one of the differential diagnosis.

Keyword

MALToma; Conjunctiva; Panuveitis; Intraocular involvement

MeSH Terms

Anterior Chamber
Conjunctiva
Diagnosis
Diagnosis, Differential
Female
Humans
Immunohistochemistry
Iris
Lymphocytes
Lymphoid Tissue
Middle Aged
Panuveitis
Visual Acuity
Vitrectomy