Korean J Hepatobiliary Pancreat Surg.  2011 Aug;15(3):164-170. 10.14701/kjhbps.2011.15.3.164.

Risk factors for the clinical course of cholecystitisin patients who undergo cholecystectomy

• Lee S
• Chung CW
• Ko KH
• Kwon SW

• KMID: 2130988
• DOI: http://doi.org/10.14701/kjhbps.2011.15.3.164

Abstract

BACKGROUNDS/AIMS
The aims of this study were to evaluate risk factors for acute cholecystitis that have been previously acknowledged and to evaluate several co-morbidities, such as hypertension, diabetes mellitus, cardiovascular disease, cerebrovascular accident and end-stage renal disease for which the prevalence rate has increased in the elderly.
METHODS
We retrospectively reviewed 611 patients who underwent laparoscopic or open cholecystectomy for cholecystitis between January 2005 and January 2010. The relationships between the clinical outcomes and the clinico-demographic factors were analyzed by univariate and multivariate analyses.
RESULTS
The diagnoses of the 611 patients who underwent laparoscopic cholecystectomy were acute cholecystitis (n=258; 42.2%) and chronic cholecystitis (n=353; 57.8%). Male gender (p<0.000), age >50 (p<0.000), fever (p<0.000), leukocytosis (p<0.000), AST elevation (p=0.009), alkaline phosphatase elevation (p<0.000) and an elevation of total bilirubin (p<0.000) were identified as risk factors for acute cholecystitis. The presence of diabetes mellitus (p=0.002) and hypertension (p=0.019) may be risk factors for acute cholecystitis.
CONCLUSIONS
For patients with risk factors for acute cholecystitis, early management, that is, early checkup and diagnosis following early cholecystectomy, is recommended before the disease progresses to an acute form of cholecystitis.

Keyword

Cholecystitis; Risk factor; Cholecystectomy

MeSH Terms

Alkaline Phosphatase
Bilirubin
Cardiovascular Diseases
Cholecystectomy
Cholecystectomy, Laparoscopic
Cholecystitis
Cholecystitis, Acute
Diabetes Mellitus
Fever
Humans
Hypertension
Kidney Failure, Chronic
Leukocytosis
Male
Prevalence
Retrospective Studies
Risk Factors
Stroke
Alkaline Phosphatase
Bilirubin

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