Allergy Asthma Immunol Res.  2012 Jan;4(1):55-57. 10.4168/aair.2012.4.1.55.

Fulminant and Fatal Multiple Organ Failure in a 12-Year-Old Boy With Mycoplasma pneumoniae Infection

Affiliations
  • 1Department of Pediatrics, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea. jsjs87@ajou.ac.kr
  • 2Department of Pediatrics, Yonsei University College of Medicine, Severance Children's Hospital, Seoul, Korea.

Abstract

Mycoplasma pneumoniae (Mp) is a unique pathogen that causes not only pulmonary but also extrapulmonary manifestations that must be rapidly diagnosed. A 12-year-old boy, with no relevant medical history, presented with fever, severe epigastric pain, and vomiting. Laboratory findings showed fulminant and cholestatic hepatitis, hemolytic anemia, thrombocytopenia, acute kidney injury, disseminated intravascular coagulopathy, acute myocardial infarction, and rhabdomyolysis. His clinical condition rapidly deteriorated during intubation and continuous renal replacement therapy. Despite intensive treatment, he did not recover. We report a case of fulminant and fatal multiple organ failure in a previously healthy boy with Mp infection, describing the possible pathomechanisms of multiple organ failure involved in the disease.

Keyword

Mycoplasma pneumoniae; multiple organ failure; rhabdomyolysis

MeSH Terms

Acute Kidney Injury
Anemia, Hemolytic
Child
Fever
Hepatitis
Humans
Intubation
Multiple Organ Failure
Mycoplasma
Mycoplasma pneumoniae
Myocardial Infarction
Pneumonia, Mycoplasma
Renal Replacement Therapy
Rhabdomyolysis
Thrombocytopenia
Vomiting

Figure

  • Figure Chest radiograms showing (A) initial status on admission (B) pleural effusion followed by thoracostomy.


Cited by  1 articles

A Child of Severe Mycoplasma pneumoniae pneumonia with Multiple Organ Failure Treated with ECMO and CRRT
Woojin Hwang, Yoonjin Lee, Eunjee Lee, Jiwon M. Lee, Hong Ryang Kil, Jae Hyeon Yu, Eun Hee Chung
Pediatr Infect Vaccine. 2019;26(1):71-79.    doi: 10.14776/piv.2019.26.e9.


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