J Korean Ophthalmol Soc.  1997 Nov;38(11):1931-1935.

Morphological Studies on Fuchs`Dystrophy

Affiliations
  • 1Department of Ophthalmology, Ewha Medical Research Center, Ewha Womans University, Seoul, Korea.

Abstract

Light andelectron microscopic findings of Fuchs`dystrophy were examined in a corneal button obtained following a penetrating keratoplasty. In light microscopic study, an avascular connective tissue was observed between the epithelial basement membrane and Bowman`s layer. Fibroblast-like cells scattered on the denuded surface of the Descemet`s membrane were found in a flat-mounted specimen examined after alizarine red and tryphan blue staining. A slightly thickened Descemet`s membrane covered with the disorganized endothelium was observed in a electron microscopy. Swollen organelles and vacuoles in the cytoplasm were found as an internal structure of the endothelium.

Keyword

Flat-mount study; Fuch`s dystrophy; light and electron microscopic study

MeSH Terms

Basement Membrane
Connective Tissue
Cytoplasm
Endothelium
Keratoplasty, Penetrating
Membranes
Microscopy, Electron
Organelles
Vacuoles
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