J Korean Ophthalmol Soc.  1995 May;36(5):752-757.

Excimer Laser Phototherapeutic Keratectomy for Experimental Fungal Keratitis

Affiliations
  • 1Department of Ophthalmology, Kosin Medical College, Korea.

Abstract

Photoablation with 193-nm excimer laser was performed on the corneal infiltration after induction of experimental Candida albicans keratitis and Aspergillus fumigatus keratitis in rabbits in order to evaluate the therapeutic effect of excimer laser. The excimer laser eradicated the corneal infiltration in all eight eyes of the C, albicans group. In the A, fumigatus group, two corneas were perforated during treatment and one cornea left the fungal hyphae in the deep corneal stroma after treatment. Though it cannot remove the hyphae completely in the deeply invaded fungal keratitis because of corneal perforation during treatment, excimer laser photoablation may be an effective technique to eradicate early, localized, superficial fungal keratitis.

Keyword

Aspergillus rumigatus keratitis; Candida albicans keratitis; Excimer laser photoablation

MeSH Terms

Aspergillus fumigatus
Candida albicans
Cornea
Corneal Perforation
Corneal Stroma
Hyphae
Keratitis*
Lasers, Excimer*
Rabbits
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