Clin Exp Otorhinolaryngol.  2015 Sep;8(3):183-188. 10.3342/ceo.2015.8.3.183.

Evaluation of Hearing and Outer Hair Cell Function of Cochlea in Patients With Psoriatic Arthritis

• Akdag M
• Ucmak D
• Ozkurt FE
• Bozkurt M
• Akkurt ZM
• Topcu I

• KMID: 2117508
• DOI: http://doi.org/10.3342/ceo.2015.8.3.183

Abstract

OBJECTIVES
The aim of this study was to investigate hearing and outer cells function in patients with psoriatic arthritis. Our investigation was a prospective case control study.
METHODS
A total of 31 psoriatic arthritis patients (62 ears) and 31 healthy control subjects (62 ears) were enrolled in the study. We investigated hearing changes of patients and controls via pure tone audiometry, speech discrimination scores, tympanometry, acoustic reflex, and transient product otoacoustic emission.
RESULTS
The mean age of psoriatic arthritis patients was 36.1+/-8.5 years (range, 14 to 62 years). The average age of the control group was 37.9+/-8.1 years (range, 16 to 62 years). There were statistically significant differences between pure tone audiometry in all frequencies and right and left emission at the 4.0 and 1.0 in psoriatic arthritis patients versus controls (P<0.05). This difference was evident, especially at high frequencies. There was no statistically significant difference between the ages and genders of the patient and control groups (P>0.05). Both audiological and otoacoustic emissions were not significantly different between right and left ear (P>0.05).
CONCLUSION
Based on the audiological and otoacoustic findings; it is likely that the cochlear outer hair cells become subtly damaged in psoriatic arthritis patients, consequently leading to changes in hearing thresholds. These data suggest that it is important to screen psoriatic arthritis patients for hearing changes with otoacoustic emissions and audiologic tests regularly.

Keyword

Arthritis, Psoriatic; Hearing; Audiometry, Pure Tone; Otoacoustic Emissions, Spontaneous; Acoustic Impedance Tests

MeSH Terms

Acoustic Impedance Tests
Arthritis, Psoriatic*
Audiometry
Audiometry, Pure-Tone
Audiometry, Speech
Case-Control Studies
Cochlea*
Discrimination (Psychology)
Ear
Hair*
Hearing*
Humans
Otoacoustic Emissions, Spontaneous
Prospective Studies
Reflex, Acoustic

Figure

• 

  Fig. 1 Right audiometric graphic of frequency and pure tone thresholds of patient and control groups. Frequency of right audiometry: 250 Hz, P<0.001; 500 Hz, P<0.001; 1,000 Hz, P=0.011; 2,000 Hz, P<0.001; 4,000 Hz, P=0.001; 6,000 Hz, P<0.001.

• 

  Fig. 2 Left audiometric graphic of frequency and pure tone thresholds of patient and control groups. Frequency of left audiometry: 250 Hz, P=0.013; 500 Hz, P=0.023; 1,000 Hz, P=0.007; 2,000 Hz, P=0.002; 4,000 Hz, P=0.002; 6,000 Hz, P<0.001.

• 

  Fig. 3 Right otoacoustic emission graphic of frequency and sound noise ratio changes of patient and control groups. Frequency of right otoacoustic emission: 1.0 Hz, P=0.053; 1.4 Hz, P=0.683; 2.0 Hz, P=0.989; 2.8 Hz, P=0.714; 4.0 Hz, P=0.024. Mann-Whitney U-test.

• 

  Fig. 4 Left otoacoustic emission graphic of frequency and sound noise ratio changes of patient and control groups. Frequency of left otoacoustic emission: 1.0 Hz, P=0.005; 1.4 Hz, P=0.213; 2.0 Hz, P=0.357; 2.8 Hz, P=0.212; 4.0 Hz, P=0.076. Mann-Whitney U-test.

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