J Korean Burn Soc.  2015 Jun;18(1):7-12. 10.0000/jkbs.2015.18.1.7.

The Comparison of Blood Acid-Base Changes in Severe Burn Patients Resuscitation with Hartmann Solution and Plasma Solution-A

• Lee SJ
• Cho IS
• Park YT
• Jung YM
• Choi SY
• Park JH
• Yoo KT

• KMID: 2117480
• DOI: http://doi.org/10.0000/jkbs.2015.18.1.7

Abstract

PURPOSE
Intravenous infusion of crystalloid solution is very important in the treatment of severe burn patients. But variable blood acid-base differences can be induced due to crystalloids. The aim of this study was to compare, in severe burn patients, the effects of two balanced fluids (Hartmann solution and plasma solution-A) on blood chemical differences.
METHODS
A retrospective review was performed on 21 patients from January 2010 to December 2012 who admitted as severe burn patients to KEPCO Medical Center burn care unit. One group was resuscitated with Hartmann solution according to Parkland formula. The other one was resuscitated with plasma solution-A.
RESULTS
21 patients were enrolled. 14 patients belonged to plasma solution-A group and 7 patients belonged to Hartmann solution group. Bicarbonate, pH, serum lactate and serum electrolytes showed no statistic differences between plasma solution-A and Hartmann solution group (P>0.05). As time went by, pH and bicarbonate increased and serum lactate level decreased in both group.
CONCLUSION
In this study, plasma solution-A had equally alkalinizing effect as Hartmann solution in severe burn patient resuscitation.

Keyword

Burn; Plasma solution-A; Hartmann solution; Metabolic acidosis

MeSH Terms

Acidosis
Burns*
Electrolytes
Humans
Hydrogen-Ion Concentration
Infusions, Intravenous
Lactic Acid
Plasma*
Resuscitation*
Retrospective Studies
Electrolytes
Lactic Acid