J Korean Radiol Soc.
1995 Dec;33(6):875-881.
Necrotizing Pneumonia: CT Findings & its Clinical Significance
Abstract
- PURPOSE
To analyze CT and follow-up chest radiographic findings in patients with necrotizing pneumonia
and to evaluate clinical significance of the extent of necrosis.
MATERIALS AND METHODS
We reviewed medical records and retrospectively analysed CT scans and
follow-up chest radiographs of 22 patients with necrotizing pneumonia, confirmed by biopsy(n=7) and culture
(n=15). Inclusion criteria for necrotizing pneumonia was necrotic low attenuation, with or without cavitation on
postcontrast enhanced CT scan. The study group included 15 men and seven women, aged 11-66 years (average: 47years).
RESULTS
The pathogens of necrotizing pneumonia were Klebsiella spp(n=7), Enterobacter spp(n=5), Actinomyces
spp(n=4), Pseudomonas spp(n=4), Nocardia spp(n=4), and others(n=5). Average duration of pneumonia
was 4.1 months. On CT scan, pneumonic consolidations were well-marginated in 14 patients and there
were cavities on initial CT scan in 16 cases. Margins of the necrotic portion on CT scan were well-demarcated
in majority of the patients(16/22). Low attenuation areas on initial CT scan resulted in cavitation, fibrosis and
volume loss as shown on follow-up chest radiographs. The larger the necrotic areas on CT, the more the volume
loss was.
CONCLUSION
CT findings of necrotizing pneumonia were well-marginated air-space consolidation with low
attenuation area, with or without cavity. The extent of necrotic area was closely related with the degree of
fibrotic change later on. CT is important tool for diagnosis and prediction of parenchymal damage in necrotizing
pneumonia.