A Case of the Poorly Differentiated Metastatic Adenocarcinoma with Unknown Origin in Stomach

Ahn, Young Soo; Choi, Jae Dong; Lee, Joon Seong; Lee, Moon Sung; Kim, Jin Hong; Cho, Sung Won; Shim, Chan Sup

Abstract

Metastatic cancer with unknown origin(MUO) is not a rare disease in general hospitals and cancer therapeutic centers with a overall incidence of 4-10%. Although there is no universally accepted definition of MUO, an adequate definition includes any case with histologically confirmed metaetatie Carcinoma in which no primary site has been identified inspite of a thorough history; careful physical examinations, and screening tests. Tha diagnostic procedures are important because of therapeutic plans and the prognosis are more dependent upon the cancer tissue type rather than any other factors. Metastasis to the stomach is much more rare occasion in clinical situations of cancer metastasis. We experienced a case of poorly differentiated metastatic adenocarcinoma in stomach which showed: multiple doughnut-like submucosal tumors with central ulceration by gastrofiberscopy and could not identified the primary site in spite of a thorough diagnostic studies including immunochemical histology.