Korean J Thorac Cardiovasc Surg.
2014 Apr;47(2):133-136.
Normothermic Cardiac Surgery with Warm Blood Cardioplegia in Patient with Cold Agglutinins
- Affiliations
-
- 1Department of Thoracic and Cardiovascular Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Korea. ytquark@khnmc.or.kr
- 2Department of Thoracic and Cardiovascular Surgery, Chungbuk National University College of Medicine, Korea.
Abstract
- Cold agglutinins are predominately immunoglobulin M autoantibodies that react at cold temperatures with surface antigens on the red blood cell. This can lead to hemagglutination at low temperatures, followed by complement fixation and subsequent hemolysis on rewarming. Development of hemagglutination or hemolysis in patients with cold agglutinins is a risk of cardiac surgery under hypothermia. In addition, there is the potential for intracoronary hemagglutination with inadequate distribution of cardioplegic solutions, thrombosis, embolism, ischemia, or infarction. We report a patient with incidentally detected cold agglutinin who underwent normothermic cardiac surgery with warm blood cardioplegia.
MeSH Terms
-
Agglutinins*
Antigens, Surface
Autoantibodies
Cardioplegic Solutions
Cardiopulmonary Bypass
Cold Temperature
Complement System Proteins
Embolism
Erythrocytes
Heart Arrest, Induced*
Hemagglutination
Hemolysis
Humans
Hypothermia
Immunoglobulin M
Infarction
Ischemia
Rewarming
Thoracic Surgery*
Thrombosis
Agglutinins
Antigens, Surface
Autoantibodies
Cardioplegic Solutions
Complement System Proteins
Immunoglobulin M
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Anesthesia for Cardiac Surgery in a Patient with Unsuspected Cold Agglutinin Disease
- Open Heart Surgery in Patient with Incidentally Detected Cold Agglutinin: A case report
- Clinical Experiences of Continuous Warm Blood Cardioplegia: Valvular Heart Surgery
- Clinical Experiences of Continuous Tepid Blood Cardioplegia; Valvular Heart Surgery
- Anesthetic Management for the Open Heart Surgery in a Patient with Cold Agglutinin Disease: Case report
