Korean J Thorac Cardiovasc Surg.  2001 Oct;34(10):797-799.

Open Heart Surgery in Patient with Incidentally Detected Cold Agglutinin: A case report

Affiliations
  • 1Department of Cardiovascular surgery, Yonsei Cardiovascular center, Yonsei Uniuersity college of Medicine, Seoul, Korea. kjy@yumc.yonsei.ac.kr

Abstract

Open heart surgery with hypothermia in patients with cold agglutinin can cause severe complications by hemolysis and hemagglutination of red blood cells. A 41 year-old male patient with mitral stenosis was admitted due to fever and cough. After antibiotics treatment, he was scheduled to undergo mitral valve replacement. In the operation room, we found agglutination of blood cardioplegia during lowering temperature of cardioplegia. And then, the cardioplegia was changed to warm cardioplegia and the operation was performed under normothermia due to the suspicion of the cold reactive protein. The operation was performed uneventfully. Postoperatively, cold agglutinin was confirmed by immunochemistry of the patient's serum.

Keyword

Agglutinins; Cardiopulmonary bypass; Open heart surgery

MeSH Terms

Adult
Agglutination
Agglutinins
Anti-Bacterial Agents
Cardiopulmonary Bypass
Cough
Erythrocytes
Fever
Heart Arrest, Induced
Heart*
Hemagglutination
Hemolysis
Humans
Hypothermia
Immunochemistry
Male
Mitral Valve
Mitral Valve Stenosis
Thoracic Surgery*
Agglutinins
Anti-Bacterial Agents
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