Korean J Thorac Cardiovasc Surg.  1998 May;31(5):549-551.

Acute Esophageal Stricture After Induction Chemotherapy for Acute Leukemi: Report of a case

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Maryknoll Hospital, Korea.
  • 2Department of Internal Medicine, Maryknoll Hospital, Korea.
  • 3Depatment of Clinical Pathology, Maryknoll Hospital, Korea.
  • 4Department of Anatomic Pathology, Maryknoll Hospital, Korea.

Abstract

Although dysphagia in patients with acute leukemia is usually related to reflux esophagitis, infectious esophagitis, chemotherapy1) and leukemic infiltration2), acute esophageal stricture resulting from chemotherapy in the patient with leukemia is very rare. A 40-year-old man with acute myelogenous leukemia was admitted for operation of esophageal stricture which was developed within 1 month of chemotherapy. An esophagectomy and esophagogastrostomy with pyloroplasty was carried out. Histology showed mucosal infiltration of mononuclear cells and transmural fibrosis involving submucosa and the muscle layer.

Keyword

esophageal stricture; leukemia

MeSH Terms

Adult
Deglutition Disorders
Drug Therapy
Esophageal Stenosis*
Esophagectomy
Esophagitis
Esophagitis, Peptic
Fibrosis
Humans
Induction Chemotherapy*
Leukemia
Leukemia, Myeloid, Acute
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