J Korean Ophthalmol Soc.  2002 Mar;43(3):498-508.

Clinical Analysis of Hypofluorescent Spots in Indocyanine Green Angiography

• Youn SH
• Lee JH
• Kim HK

Abstract

PURPOSE: We observed many cases which showed hypofluorescent spots in indocyanine green angiography (ICGA) at the late phase as well as white dot syndrome, so we analyzed for types and causes of these.
METHODS
we analyzed the color photographs, fluorescein angiographs (FAG) and ICGA of the 21 patients (39 eyes) who have noted hypofluorescent spots at the late phase retrospectively.
RESULTS
The hypofluorescent spots in ICGA could be classified into two types. The first is that which seen hypofluorescence from the early phase and clearly to the late phase and the second, relatively lighter dark spots which appeared after midphase and is seen in the late phase. But when we analyze these together with ophthalmologic findings and FAG, we found out that the lesion could not be found in the retina and FAG or that it is noted as hyperfluorescence or hypofluorescence in the early and late phase of FAG. So the causes were thought to be variable.
CONCLUSIONS
We could find hypofluorescent spots in the late phase of ICGA in the lesions which were classified as white dot syndrome in the past as well as presented normal finding in the retina and FAG and they had variable morphologies and causes.

Keyword

Hypofluorescent spots; Indocyanine green angiography; White dot syndrome

MeSH Terms

Angiography*
Fluorescein
Humans
Indocyanine Green*
Retina
Retrospective Studies
Fluorescein
Indocyanine Green