J Korean Ophthalmol Soc.
2001 Sep;42(9):1354-1361.
Morphological Study of a New Orbital Implant: Hydroxyapatite-Coated Porous Alumina in Rabbit
- Affiliations
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- 1The Institute of Vision Research, Yonsei University College of Medicine.
- 2Department of Ophthalmology, Yonsei University College of Medicine.
Abstract
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PURPOSE: We evaluated the morphologic change of the hydroxyapatite(HA)-coated porous alumina as a new orbital implant when it was used in rabbit.
METHODS
After evisceration of 18 eyes of 18 New Zealand white rabbits, we implanted 12 mm-diameter-sized HA-coated porous alumina with different pore sizes; 300, 500, and 800 micrometer, and then the implants were extracted back to evaluate their morphologic change according to different time interval; 2, 4, and 12 weeks.
RESULTS
Fibrovascularization was noted at periphery of the implant 2 weeks after implantation in all of the three groups, and to the center of the implant 4 and 12 weeks after implantation. This fibrova-scularization was most predominant in 500 micrometerpore-sized group compared to the rest two groups.
CONCLUSIONS
HA-coated porous alumina showed similar appearance of fibrovascularization with relatively more affordable price and easy manufacture, compared to the other porous implants.
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