J Korean Ophthalmol Soc.  1974 Mar;15(1):9-15.

Experimental Studies on the Sterilization of The Soft Contact Lens

Affiliations
  • 1Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

Mycon-soft lenses (made by Tokyo contact lens Co., Japan) were contaminated experimentally with coagulase positive staphylococcus aureus and pseudomonas aeruginosa and sterilizing effects of some disinfectants (3% H2O2, 6% H2O2, 0.1% Benzalkonium and 1:1000 Merthiolate solutions) on those contaminated lenses were studied. The following results were obtained: 1. SCL contaminated with staphylcoccus were sterilized by soaking in 3% H2O2, 6% H2O2, or 1:1000 Merthiolate solution over 15 minutes, and in 0.1 Benzalkonium over 60 minutes. 2. SCL contaminated with pseudomonas aeruginosa were sterilizd by soaking in 6% H2O2 over 15 minutes, in 1:1000 MerthioJate solution over 60 minutes, in 3% H2O2 over 60 minutes, but no sterilization was obtained by soaking in 0.1 % Benzalkonium solution for less than 180 minutes. 3. No signs of irritation were noted on rabbit corneas fitted with SCL after soaking in 3% H2O2 or 6% H2O2 for 15 minutes followed by soaking in 20cc of normal saline for 15 minutes.


MeSH Terms

Benzalkonium Compounds
Coagulase
Contact Lenses, Hydrophilic*
Cornea
Disinfectants
Pseudomonas aeruginosa
Staphylococcus aureus
Sterilization*
Thimerosal
Benzalkonium Compounds
Coagulase
Disinfectants
Thimerosal
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