J Korean Pediatr Soc.  2000 Dec;43(12):1621-1625.

A Case of Congenital Epulis of the Newborn

Affiliations
  • 1Department of Pediatrics, College of Medicine, Chosun University, Kwangju, Korea.
  • 2Department of Plastic Surgery, College of Medicine, Chosun University, Kwangju, Korea.
  • 3Department of Pathology, College of Medicine, Chosun University, Kwangju, Korea.

Abstract

Congenital epulis of the newborn refers to a very rare gingival tumor that occurs along the anterior alveolar ridge in newborn infants. We report a neonate with 3*2*1.5cm mass protruding from the mouth. This was a pinky, red solid pedunculated mass, attached to the maxillar left canine region of the alveolus at birth. The tumor's large size partially obliterated the oral cavity and caused oral feeding difficulty but did not cause respiratory problems. We described the postnatal MR imaging findings, electromicroscopic, histochemical and immunohistochemical studies of this tumor in order to search for the histogenesis of the tumor. In our case, histochemically, individual tumor cells contained numerous PAS positive cytoplasmic granules. Immunohistochemically, strong and diffuse cytoplasmic staining for vimentin and NSE was observed. Staining with S-100 protein, cytokeratin, desmin, CEA, factor VIII-related antigen, lysozyme, EMA were negative. After total excision of the lesion in our case, we had no complication or recurrence either early or late(up to one year).

Keyword

Congenital epulis; Immunohistochemical studies

MeSH Terms

Alveolar Process
Cytoplasm
Cytoplasmic Granules
Desmin
Gingival Neoplasms*
Humans
Infant, Newborn*
Keratins
Magnetic Resonance Imaging
Mouth
Muramidase
Parturition
Recurrence
S100 Proteins
Vimentin
von Willebrand Factor
Desmin
Keratins
Muramidase
S100 Proteins
Vimentin
von Willebrand Factor
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