J Korean Soc Neonatol.  2011 Nov;18(2):383-386. 10.5385/jksn.2011.18.2.383.

A Case of Acrodermatitis Enteropathica with Normal Serum Zinc Level in a Breastfed Preterm Infant

Affiliations
  • 1Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea. leejmd@chol.com
  • 2Department of Dermatology, College of Medicine, Korea University, Seoul, Korea.
  • 3Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.

Abstract

Acrodermatitis enteropathica due to zinc deficiency is characterized by periorificial dermatitis, alopecia, and intractable diarrhea. Here we report a case of transient acrodermatitis enteropathica in a 2-month-old preterm infant, whose skin is erythematous, scaly, eczematous, with an eruption starting from the periorificial area. While her serum zinc level was normal at 118.2 ug/dL, the serum alkaline phosphatase level was low at 48 IU/L and the serum alkaline phosphatase level get increased concordant with clinical improvement after zinc supplementation. Hence, this case shows that the diagnosis of zinc deficiency can be aided with a low level of serum alkaline phoaphatase although serum zinc level is normal.

Keyword

Acrodermatitis enteropathica; Alkaline phosphatase; Zinc deficiency; Periorificial dermatitis

MeSH Terms

Acrodermatitis
Alkaline Phosphatase
Alopecia
Dermatitis
Diarrhea
Humans
Infant
Infant, Newborn
Infant, Premature
Skin
Zinc
Acrodermatitis
Alkaline Phosphatase
Zinc
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