J Korean Soc Radiol.  2010 Sep;63(3):261-265. 10.3348/jksr.2010.63.3.261.

Inflammatory Myofibroblastic Tumor of the Bladder: Report of Two Cases

• Kim H
• Oh SN
• Rha SE
• Jung SE
• Lee YJ
• Byun JY
• Jung CK
• Choi YJ

• KMID: 2097903
• DOI: http://doi.org/10.3348/jksr.2010.63.3.261

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare condition of unknown origin. Pathologically, the lesion is composed of myofibroblastic spindle cells accompanied by an inflammatory infiltrate of plasma cells, lymphocytes, and eosinophils. We report two cases of inflammatory myofibroblastic tumor of the bladder which showed different imaging features and was falsely diagnosed as malignant tumors. We discuss the imaging findings along with a literature review.

MeSH Terms

Eosinophils
Lymphocytes
Myofibroblasts
Plasma Cells
Urinary Bladder
Urinary Bladder Diseases

Figure

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  Fig. 1 A 28-year-old woman presented with inflammatory myofibroblastic tumor. Color Doppler sonogram (A) shows a hypoechoic and hypervascular mass in the anterior wall of the bladder dome. Contrast-enhanced axial (B) and sagittal (C) CT scans show a well contrast enhancing portion (long arrow in B and C) on the right side of the mass. Moreover, a poorly enhancing area (asterisk) was evident in the left posterior portion. An irregular-shaped lesion (open arrow in B) was seen in the dependent portion of the contrast-filled bladder, suggesting hematoma. Microphotography (D) shows a proliferation of atypical spindle cells (arrows) and inflammatory cell infiltration in a myxoid background.

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  Fig. 2 A 51-year-old woman with an inflammatory myofibroblastic tumor. Dynamic contrast-enhanced axial CT scans show a rounded mass (arrows in A-C) with strong enhancement on arterial (B) and portal (C) phase, arising from the left lateral aspect of the bladder. Note the diffuse and irregular bladder wall thickening. Microphotography (D) shows a proliferation of atypical spindle cells (arrows) and inflammatory cell infiltration with a myxoid background.

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