J Korean Soc Ther Radiol.  1993 Dec;11(2):331-336.

Treatment of Locally Advanced Pancreatic Cancer

• Kim DY
• Ha SW

Abstract

From January 1981 to December 1991, forty patients with localized advanced carcinoma of the pancreas were treated at the Department of Therapeutic Radiology, Seoul National University Hospital. The treatment protocol consisted of two split course external radiation therapy with each 2000 cGy over two weeks separated by two week rest period. Intravenous 5-fluorouracil (5-FU) was administered on the first three days of each radiotherapy course. Twenty three of these patients were treated by maintenance 5-FU or FAM (5-FU, adriamycin, mitomycin) chemotherapy. Median survival was 9 months and the 2-year survival rate was 10.0%. Good prognostic indicators were good performance status, palliative bypass surgery and tumor located in the head of pancreas.

Keyword

Carcinoma of the pancreas; Radiotherapy; Chemotherapy

MeSH Terms

Clinical Protocols
Doxorubicin
Drug Therapy
Fluorouracil
Head
Humans
Pancreas
Pancreatic Neoplasms*
Radiation Oncology
Radiotherapy
Seoul
Survival Rate
Doxorubicin
Fluorouracil