J Korean Soc Transplant.
1999 Dec;13(2):337-344.
A Case of Aspergillous and Cytomegalovirus Pneumonia after Renal Transplantation
- Affiliations
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- 1Department of Internal Medicine, Chonbuk National University Medical School, Chonju, Korea. Parksk@moak.chonbuk.ac.kr
- 2Department of General Surgery, Chonbuk National University Medical School, Chonju, Korea.
- 3Department of Urology, Chonbuk National University Medical School, Chonju, Korea.
- 4Department of Thoracic, Chonbuk National University Medical School, Chonju, Korea.
- 5Department of Cardiovascular Surgery, Chonbuk National University Medical School, Chonju, Korea.
- 6Institute for Medical Sciences, Chonbuk National University Medical School, Chonju, Korea.
Abstract
- The immunosuppression significantly increases the risk for acquiring opportunistic infections due to bacteria, viruses, fungi, and protozoa. These opportunistic infections are the major source of morbidity and mortality in transplanted patients. Cytomegalovirus and Aspergillus are important infectious agents in renal transplant recipients. The onset of these diseases follows the period of maximal immunosuppression for the prevention and treatment of acute rejection. Cytomegalovirus infection can suppressed immunity in renal transplant recipient and associated with other opportunistic infections. We experienced a case of Aspergillus and Cytomegalovirus pneumonia after renal transplantation. This 45-year-old woman had undergone renal transplantation. About 1 months later, she presented with dry cough and mild fever. Chest radiographs revealed multifocal patchy and conglomerated consolidation on both lung field, especially lower lung field. The invasive aspergillosis and cytomegalovirus pneumonia was diagnosed by open lung biopsy. Her condition was progressively aggravated despite amphotericin B and ganciclovir therapy and expired 53 days after renal transplantation.
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