J Korean Soc Transplant.
2005 Jun;19(1):69-73.
Disseminated Cytomegalovirus Infection after Renal Transplantation: A Case Report
- Affiliations
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- 1Dongsan Kidney Institute, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea. k780121@dsmc.or.kr
Abstract
- Cytomegalovirus (CMV) remains an important pathogen in organ transplant recipients, and ganciclovir has been the antiviral agent of choice both for prevention and treatment of CMV disease. Recently ganciclovir-resistant cytomegalovirus has been reported with increasing frequency in organ transplant recipient and is an emerging clinical problem in transplant recipients. Ganciclovir-resistant CMV infection has been associated with clinical progression of CMV disease and high mortality even with foscarnet therapy. We report here a case of disseminated ganciclovir-resistant CMV disease in a 34-year-old renal transplant recipient, who died of multiorgan failure despite treatment with both ganciclovir and foscarnet.