Korean J Anesthesiol.  2005 Jan;48(1):10-14. 10.4097/kjae.2005.48.1.10.

A Comparison of the Effects of Propofol and Sevoflurane Anesthesias on Intraocular Pressure during Laparoscopic Hysterectomy

• Son YS
• Oh SC
• Chung KD
• Kim KH
• Yoon KJ

• KMID: 2091947
• DOI: http://doi.org/10.4097/kjae.2005.48.1.10

Abstract

BACKGROUND: Laparoscopic surgery in the Trendelenburg position affects the cardiopulmonary system and may also influence intraocular pressure (IOP). The purpose of this study was to compare the effects of propofol and sevoflurane anesthesias on IOP change during laparoscopic hysterectomy.
METHODS
Thirty-one women were randomly allocated to either a propofol (P-group, n = 15) intravenous anesthesia group or a sevoflurane (S-group, n = 16) inhaled anesthesia group with fentanyl-N2O/O2-vecuronium. Heart rate, mean arterial pressure, plateau airway pressure, ETCO2, and IOP were measured before induction (T1), 10 min after induction (T2), 10 min after pneumoperitoneum in the Trendelenburg position (T3), and 5 min after pneumoperitoneum deflation in the horizontal position (T4).
RESULTS
IOP was significantly decreased in both groups after induction. IOP was increased in both groups after pneumoperitoneum in the Trendelenburg position, but IOP in the sevoflurane group was significantly higher than that in the propofol group.
CONCLUSIONS
Propofol intravenenous anesthesia may be a better choice for IOP control during laparoscopic surgery.

Keyword

intraocular pressure; laparoscopic surgery; propofol; sevoflurane; trendelenburg position

MeSH Terms

Anesthesia*
Anesthesia, Intravenous
Arterial Pressure
Female
Head-Down Tilt
Heart Rate
Humans
Hysterectomy*
Intraocular Pressure*
Laparoscopy
Pneumoperitoneum
Propofol*
Propofol