Korean J Anesthesiol.  1996 Nov;31(5):658-661. 10.4097/kjae.1996.31.5.658.

Anesthetic Management of Polycythemia Vera Patient with Shoulder Joint Fracture

Affiliations
  • 1Department of Anesthesiology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

Polycythemia vera is a hematologic malignancy characterized by excessive proliferation of erythroid, myeloid and megakaryocytic elements within bone marrow, resulting in increased red cell mass, frequently leukocytosis and thrombocytosis. Patients with absolute erythrocytosis can be categorized into primary; those in whom excessive production of red cells results from a disorder intrinsic to the erythroid progenitor cells of bone marrow, or secondary; from excessive stimulation of an otherwise normal marrow by substance such as erythropoietin. Polycythemia vera is a disease process in which control prior to surgery decreases the frequency of perioperative complications. Surgery was postponed on an 61-year-old female patient found to have a hematocrit of 59%. She was phlebotomized and treated with hydroxyurea. Her hematocrit was decreased to 43%. General anesthesia was maintained with N2O-O2-enflurane after tracheal intubation. No thrombotic or bleeding problem was developed and she was discharged without complication at 14th day after operation.

Keyword

Blood Polycythemia; Complication thrombosis; hemorrhage

MeSH Terms

Anesthesia, General
Bone Marrow
Erythrocyte Volume
Erythroid Precursor Cells
Erythropoietin
Female
Hematocrit
Hematologic Neoplasms
Hemorrhage
Humans
Hydroxyurea
Intubation
Leukocytosis
Middle Aged
Polycythemia Vera*
Polycythemia*
Shoulder Joint*
Shoulder*
Thrombocytosis
Erythropoietin
Hydroxyurea
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