Korean J Anesthesiol.  1987 Dec;20(6):728-732. 10.4097/kjae.1987.20.6.728.

The Effects of Oral Premedication on Children

• Kim SD
• Yang HK
• Lee KH
• Kim CD

• KMID: 2090487
• DOI: http://doi.org/10.4097/kjae.1987.20.6.728

Abstract

The effects of oral premedication with diazepam and atropine were evaluated. We made three kinds of syrup which were composed of diazepam 0.3mg/0.5cc, diazepam 0.3 mg mixed with atropine 0.001 mg in 0.5cc and diazepam 0.3mg mixed with atropine 0.03mg in 0.5cc, respectively. The 1st was administered to Group l (n=21), the second to group ll (n=21) and the last to group lll (n= 24) one and half to two hours before induction of anesthesia. Each child received 0.5 cc/kg. On arrival at pediatric operating room, anxiety levels, vital signs, antisalivatory effect and side effects were checked. The attitude of children was evaluated just before induction of anesthesia. In group land lll, slight elevation of diastolic blood pressure was noticed. The satisfaotory levels, checked by anxiety level O, were 86% in group l, 90% in group ll and 79% in group lll. The altitudes in the operating rooms just before induction of anesthesia were satisfactory and cooperative in 77 %, 81%, and 87% of patients in group l, ll and lll, respectively. Antisalivatory effect was not good in group l, but satisfactory in 82% and 75% of cases in group ll and lll. But side effect was present in 25% of cases in group ll and lll, in spite of 10% in group l. So we can conclude that preoperative oral diazepam in a dose of 0.3mg/0.5cc/kg is very good for the reduction of anxiety and the additiopn of atropine may increase the incidence of side effects. Threefore we recommend parentreral belladonna alkaloids just before induction instead of preoperative oral medication.

MeSH Terms

Altitude
Anesthesia
Anxiety
Atropine
Belladonna Alkaloids
Blood Pressure
Child*
Diazepam
Humans
Incidence
Operating Rooms
Premedication*
Vital Signs
Atropine
Belladonna Alkaloids
Diazepam