Korean J Dermatol.
2013 Jul;51(7):548-551.
A Case of Clear Cell Basal Cell Carcinoma
- Affiliations
-
- 1Department of Dermatology, Wonkwang University School of Medicine, Iksan, Korea. sdpark@wku.ac.kr
- 2Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea.
Abstract
- Clear cell basal cell carcinoma is a rare histological variant of basal cell carcinoma, which is characterized by a variable component of clear cells. We report a case of clear cell basal cell carcinoma in a 53-year-old Caucasian male presented with a red 0.7x0.6 cm sized nodule with central bleeding on left cheek for 2 years. Histological examinations showed multiple dermal tumor lobules nested with basaloid cells of a peripheral palisading pattern. In addition, prominent clear cell changes were observed in the center of large nests. The clear cells showed a single large vacuole in their eosinophilic and granular cytoplasm with eccentric condensed nucleus. The clear tumor cells was stained with periodic acid Schiff and showed incomplete diastase-resistance. Intercellular mucin staining with alcian blue was positive. The tumor was successfully treated with Mohs micrographic surgery and no recurrence has been observed for 6 months.
