Korean J Dermatol.  2011 Aug;49(8):661-669.

TRUE Test in Patients with Contact Dermatitis: A Multicenter Study

Affiliations
  • 1Department of Dermatology, Ewha Womans University School of Medicine, Korea. hychoi@ewha.ac.kr
  • 2Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Korea.
  • 3Department of Dermatology, Kyungpook National University School of Medicine, Korea.
  • 4Department of Dermatology, Korea.Chonnam National University Medical School, Korea.
  • 5Department of Dermatology, Gangnam Severance Hospital, Yonsei University School of Medicine, Korea.
  • 6Department of Dermatology, Hanyang University School of Medicine, Korea.
  • 7Department of Dermatology, University of Ulsan School of Medicine, Korea.
  • 8Department of Dermatology, National Medical Center, Korea.
  • 9Department of Dermatology, Korea University School of Medicine, Korea.
  • 10Department of Dermatology, Inha University School of Medicine, Korea.
  • 11Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea.
  • 12Department of Dermatology, Seoul National University School of Medicine, Korea.
  • 13Department of Dermatology, Severance Hospital, Yonsei University School of Medicine, Korea.
  • 14Hallym University School of Medicine, Korea.
  • 15Chung Ang University School of Medicine, Korea.

Abstract

BACKGROUND
The TRUE test is a commercially available ready-to-apply patch test widely used in many countries, but no large-scale study is available on the TRUE test in Korea.
OBJECTIVE
The purpose of this study was to analyze the type, frequency, and changes in the common contact allergens in Korea using the TRUE test.
METHODS
From January 2009 to March 2010, TRUE tests were performed on patients with contact dermatitis at the Departments of Dermatology of 15 hospitals. The epidemiological findings of patients, and the results of the patch tests were analyzed.
RESULTS
In total, 795 patch tested cases (246 males, 549 females) were compiled and analyzed. The oldest age distribution was the third decade in both males and females, and housewives and office-workers were the most common jobs, comprising 29.7% and 19.8% of the occupations, respectively. Overall, 65.1% of patients had at least one positive reaction, and the most common allergens were nickel sulfate (34.1%), thimerosal (12.6%), cobalt chloride (11.1%), and p-phenylenediamine (8.4%), in order of frequency. A univariate analysis of multiple variables including age, gender, occupation, and affected sites was conducted and a comparison with a previous multicenter study was also analyzed.
CONCLUSION
These results provide the basis for use of the TRUE test in patients with contact dermatitis in Korea.

Keyword

Contact dermatitis; Patch test; TRUE test

MeSH Terms

Age Distribution
Allergens
Cobalt
Dermatitis, Contact
Dermatology
Female
Humans
Korea
Male
Nickel
Occupations
Patch Tests
Phenylenediamines
Thimerosal
Allergens
Cobalt
Nickel
Phenylenediamines
Thimerosal
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